{"id":34579,"date":"2024-12-10T18:02:45","date_gmt":"2024-12-10T16:02:45","guid":{"rendered":"https:\/\/neuronup.com\/br\/?page_id=34579"},"modified":"2026-10-07T01:00:28","modified_gmt":"2026-10-06T23:00:28","slug":"doenca-de-parkinson","status":"publish","type":"page","link":"https:\/\/neuronup.com\/br\/neurorreabilitacao\/doencas-neurodegenerativas\/doenca-de-parkinson\/","title":{"rendered":"Doen\u00e7a de Parkinson"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">A <strong>doen\u00e7a de Parkinson<\/strong> \u00e9 classificada dentro dos transtornos do movimento, mas hoje sabemos que \u00e9 <strong>muito mais do que isso<\/strong>. Trata-se de uma <strong>doen\u00e7a neurodegenerativa cr\u00f4nica e progressiva<\/strong> que, al\u00e9m de alterar o controle motor, pode provocar <strong>sintomas cognitivos, emocionais, do sono, auton\u00f4micos e sensoriais<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Seu impacto n\u00e3o se limita \u00e0 mobilidade, podendo afetar de forma importante a <strong>autonomia e a qualidade de vida<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">O que acontece no c\u00e9rebro?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A origem do Parkinson est\u00e1 relacionada \u00e0 <strong>morte progressiva de neur\u00f4nios dopamin\u00e9rgicos<\/strong> na <strong>subst\u00e2ncia negra (pars compacta)<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Esses neur\u00f4nios fazem parte da <strong>via nigroestriatal<\/strong>, essencial para regular os <strong>g\u00e2nglios da base<\/strong> e a <strong>fluidez do movimento<\/strong>. A diminui\u00e7\u00e3o da dopamina provoca uma <strong>perda de coordena\u00e7\u00e3o autom\u00e1tica<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Al\u00e9m disso, observa-se <strong>ac\u00famulo de alfa-sinucle\u00edna<\/strong> (corpos de Lewy) e altera\u00e7\u00f5es em outros neurotransmissores como <strong>serotonina, noradrenalina e acetilcolina<\/strong>, o que explica os <strong>sintomas n\u00e3o motores<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Causas e fatores de risco<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">O Parkinson \u00e9 uma <strong>doen\u00e7a multifatorial<\/strong>, na qual influem:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Fatores gen\u00e9ticos<\/strong> (LRRK2, GBA1, SNCA)<\/li>\n\n\n\n<li><strong>Fatores ambientais<\/strong> (como pesticidas)<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Na maioria dos casos n\u00e3o existe uma causa \u00fanica, mas uma <strong>combina\u00e7\u00e3o de predisposi\u00e7\u00e3o biol\u00f3gica e ambiente<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Impacto e preval\u00eancia<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">O Parkinson \u00e9 uma das doen\u00e7as neurol\u00f3gicas <strong>que mais est\u00e1 crescendo<\/strong>:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Mais de 8,5 milh\u00f5es de pessoas<\/strong> afetadas no mundo<\/li>\n\n\n\n<li>Proje\u00e7\u00e3o de <strong>25,2 milh\u00f5es em 2050<\/strong><\/li>\n\n\n\n<li>Na Espanha: <strong>200.000 pessoas<\/strong> e <strong>10.000 novos casos por ano<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">O diagn\u00f3stico pode atrasar entre <strong>1 e 3 anos<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Sintomas motores<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Bradicinesia<\/strong> (lentid\u00e3o dos movimentos)<\/li>\n\n\n\n<li><strong>Redu\u00e7\u00e3o do movimento autom\u00e1tico<\/strong><\/li>\n\n\n\n<li><strong>Tremor de repouso<\/strong><\/li>\n\n\n\n<li><strong>Rigidez muscular<\/strong><\/li>\n\n\n\n<li><strong>Instabilidade postural<\/strong> e risco de quedas<\/li>\n\n\n\n<li><strong>Dificuldade na motricidade fina<\/strong><\/li>\n\n\n\n<li><strong>Altera\u00e7\u00f5es da fala<\/strong><\/li>\n\n\n\n<li><strong>Problemas de degluti\u00e7\u00e3o e sialorreia<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">A sialorreia geralmente n\u00e3o se deve ao excesso de saliva, mas \u00e0 <strong>diminui\u00e7\u00e3o da degluti\u00e7\u00e3o autom\u00e1tica<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Sintomas n\u00e3o motores<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Frequentemente aparecem at\u00e9 mesmo antes dos sintomas motores:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Ansiedade, depress\u00e3o e apatia<\/strong><\/li>\n\n\n\n<li><strong>Transtornos do sono<\/strong><\/li>\n\n\n\n<li><strong>Fadiga<\/strong><\/li>\n\n\n\n<li><strong>Constipa\u00e7\u00e3o e problemas urin\u00e1rios<\/strong><\/li>\n\n\n\n<li><strong>Disfun\u00e7\u00e3o sexual<\/strong><\/li>\n\n\n\n<li><strong>Perda do olfato<\/strong><\/li>\n\n\n\n<li><strong>Dor e sonol\u00eancia diurna<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">A <strong>depress\u00e3o pode ser uma das primeiras manifesta\u00e7\u00f5es<\/strong> em at\u00e9 40% dos casos.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Comprometimento cognitivo<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">O Parkinson tamb\u00e9m pode afetar:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Aten\u00e7\u00e3o<\/strong><\/li>\n\n\n\n<li><strong>Velocidade de processamento<\/strong><\/li>\n\n\n\n<li><strong>Mem\u00f3ria de trabalho<\/strong><\/li>\n\n\n\n<li><strong>Fun\u00e7\u00f5es executivas<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u00c9 considerado um <strong>continuum cl\u00ednico<\/strong>, no qual os sintomas cognitivos fazem parte da doen\u00e7a.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Quem \u00e9 afetado?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A idade \u00e9 o principal fator de risco:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2% das pessoas com mais de 65 anos<\/strong><\/li>\n\n\n\n<li><strong>4% das pessoas com mais de 80 anos<\/strong><\/li>\n\n\n\n<li><strong>15% dos casos em menores de 50 anos<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u00c9 <strong>mais frequente em homens<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Diagn\u00f3stico<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">O diagn\u00f3stico \u00e9 <strong>principalmente cl\u00ednico<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Para falar em parkinsonismo deve haver: <strong>bradicinesia + tremor de repouso ou rigidez<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Existem exames complementares e <strong>biomarcadores em desenvolvimento<\/strong>, mas eles n\u00e3o substituem a avalia\u00e7\u00e3o cl\u00ednica.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"1080\" height=\"1080\" src=\"https:\/\/neuronup.com\/br\/wp-content\/uploads\/2024\/12\/Sintomas-do-Parkinson-BR.webp\" alt=\"Ilustra\u00e7\u00e3o de idoso com bengala caminhando lentamente, com tremores, movimentos lentos, rigidez e altera\u00e7\u00f5es na fala e escrita.\" class=\"wp-image-33919\" style=\"width:550px\" srcset=\"https:\/\/neuronup.com\/br\/wp-content\/uploads\/2024\/12\/Sintomas-do-Parkinson-BR-24x24.webp 24w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2024\/12\/Sintomas-do-Parkinson-BR-48x48.webp 48w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2024\/12\/Sintomas-do-Parkinson-BR-80x80.webp 80w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2024\/12\/Sintomas-do-Parkinson-BR-96x96.webp 96w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2024\/12\/Sintomas-do-Parkinson-BR-150x150.webp 150w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2024\/12\/Sintomas-do-Parkinson-BR-300x300.webp 300w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2024\/12\/Sintomas-do-Parkinson-BR-768x768.webp 768w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2024\/12\/Sintomas-do-Parkinson-BR-1024x1024.webp 1024w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2024\/12\/Sintomas-do-Parkinson-BR.webp 1080w\" sizes=\"(max-width: 1080px) 100vw, 1080px\" \/><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\">Tratamento<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Atualmente: <strong>n\u00e3o existe cura nem tratamento que detenha a progress\u00e3o<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Mas h\u00e1 op\u00e7\u00f5es eficazes para controlar sintomas:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Levodopa<\/strong> (tratamento principal)<\/li>\n\n\n\n<li><strong>Agonistas dopamin\u00e9rgicos<\/strong><\/li>\n\n\n\n<li><strong>Inibidores da MAO-B<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Em fases avan\u00e7adas:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Estimula\u00e7\u00e3o cerebral profunda<\/strong><\/li>\n\n\n\n<li><strong>Terapias de infus\u00e3o cont\u00ednua<\/strong><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Neurorreabilita\u00e7\u00e3o<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">O tratamento n\u00e3o \u00e9 apenas farmacol\u00f3gico. A abordagem deve ser <strong>multidisciplinar<\/strong>:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Fisioterapia<\/strong>: marcha e equil\u00edbrio<\/li>\n\n\n\n<li><strong>Terapia ocupacional<\/strong>: autonomia<\/li>\n\n\n\n<li><strong>Fonoaudiologia<\/strong>: fala e degluti\u00e7\u00e3o<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Essa abordagem permite <strong>manter a funcionalidade e a independ\u00eancia<\/strong> por mais tempo.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">O futuro do Parkinson<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A pesquisa avan\u00e7a em:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Biomarcadores mais precisos<\/strong><\/li>\n\n\n\n<li><strong>Terapias dirigidas \u00e0 alfa-sinucle\u00edna<\/strong><\/li>\n\n\n\n<li><strong>Tratamentos modificadores da doen\u00e7a<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Algumas terapias, como o <strong>prasinezumabe<\/strong>, est\u00e3o em fases avan\u00e7adas de pesquisa.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Conclus\u00e3o<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">O Parkinson \u00e9 um <strong>transtorno neurodegenerativo complexo<\/strong>, com sintomas motores e n\u00e3o motores, que requer:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Diagn\u00f3stico precoce<\/strong><\/li>\n\n\n\n<li><strong>Acompanhamento especializado<\/strong><\/li>\n\n\n\n<li><strong>Abordagem integral<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Embora n\u00e3o tenha cura, os avan\u00e7os atuais permitem <strong>melhorar significativamente a qualidade de vida<\/strong> das pessoas que convivem com essa doen\u00e7a.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Artigos sobre a doen\u00e7a de Parkinson<\/h3>\n\n\n<div class=\"mai-grid entries entries-grid has-boxed has-image-full\" style=\"--entry-title-font-size:var(--font-size-lg);--align-text:start;--entry-meta-text-align:start;\"><div class=\"entries-wrap has-columns\" style=\"--columns-xs:1 \/ 1;--columns-sm:1 \/ 1;--columns-md:1 \/ 3;--columns-lg:1 \/ 3;--flex-xs:0 0 var(--flex-basis);--flex-sm:0 0 var(--flex-basis);--flex-md:0 0 var(--flex-basis);--flex-lg:0 0 var(--flex-basis);--column-gap:var(--spacing-lg);--row-gap:var(--spacing-lg);--align-columns:start;\"><article class=\"entry entry-grid is-column has-entry-link has-image has-image-first type-post category-parkinson tag-estimulacion-cognitiva tag-parkinson\" style=\"--entry-index:1;\" aria-label=\"Impulsividade e preju\u00edzo na tomada de decis\u00f5es na doen\u00e7a de Parkinson: um desafio cl\u00ednico crescente\" itemscope itemtype=\"https:\/\/schema.org\/CreativeWork\"><a class=\"entry-image-link\" href=\"https:\/\/neuronup.com\/br\/noticias-de-estimulacao-cognitiva\/doencas-neurodegenerativas\/parkinson\/impulsividade-e-deterioro-da-tomada-de-decisoes-na-doenca-de-parkinson-um-desafio-clinico-crescente\/\" tabindex=\"-1\" aria-hidden=\"true\"><img decoding=\"async\" width=\"400\" height=\"300\" src=\"https:\/\/neuronup.com\/br\/wp-content\/uploads\/2025\/04\/Impulsividad-y-deterioro-de-la-toma-de-decisiones-en-la-enfermedad-de-Parkinson-un-desafio-clinico-creciente-400x300.webp\" class=\"entry-image size-landscape-sm\" alt=\"Duas m\u00e3os entrela\u00e7adas em primeiro plano, uma segurando um objeto; tom de pele claro e escuro, fundo neutro.\" srcset=\"https:\/\/neuronup.com\/br\/wp-content\/uploads\/2025\/04\/Impulsividad-y-deterioro-de-la-toma-de-decisiones-en-la-enfermedad-de-Parkinson-un-desafio-clinico-creciente-400x300.webp 400w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2025\/04\/Impulsividad-y-deterioro-de-la-toma-de-decisiones-en-la-enfermedad-de-Parkinson-un-desafio-clinico-creciente-800x600.webp 800w\" sizes=\"(max-width:599px) 599px, (min-width:600px) and (max-width: 799px) 799px, (min-width:800px) and (max-width: 999px) 333px, (min-width:1000px) 400px\" \/><\/a><div class=\"entry-wrap entry-wrap-grid\"><h3 class=\"entry-title\" itemprop=\"headline\"><a class=\"entry-title-link\" href=\"https:\/\/neuronup.com\/br\/noticias-de-estimulacao-cognitiva\/doencas-neurodegenerativas\/parkinson\/impulsividade-e-deterioro-da-tomada-de-decisoes-na-doenca-de-parkinson-um-desafio-clinico-crescente\/\" rel=\"bookmark\">Impulsividade e preju\u00edzo na tomada de decis\u00f5es na doen\u00e7a de Parkinson: um desafio cl\u00ednico crescente<\/a><\/h3>\n<\/div><\/article><article class=\"entry entry-grid is-column has-entry-link has-image has-image-first type-post category-parkinson tag-parkinson tag-rehabilitacion-cognitiva\" style=\"--entry-index:2;\" aria-label=\"Reabilita\u00e7\u00e3o neuropsicol\u00f3gica na doen\u00e7a de Parkinson\" itemscope itemtype=\"https:\/\/schema.org\/CreativeWork\"><a class=\"entry-image-link\" href=\"https:\/\/neuronup.com\/br\/noticias-de-estimulacao-cognitiva\/doencas-neurodegenerativas\/parkinson\/reabilitacao-neuropsicologica-na-doenca-de-parkinson\/\" tabindex=\"-1\" aria-hidden=\"true\"><img decoding=\"async\" width=\"400\" height=\"300\" src=\"https:\/\/neuronup.com\/br\/wp-content\/uploads\/2023\/10\/Rehabilitacion-neuropsicologica-en-la-enfermedad-de-Parkinson-2-1-400x300.webp\" class=\"entry-image size-landscape-sm\" alt=\"Pessoa idosa sentada em frente a um monitor; na tela aparecem \u00edcones de vasos de plantas e a pessoa aponta um deles com o dedo.\" srcset=\"https:\/\/neuronup.com\/br\/wp-content\/uploads\/2023\/10\/Rehabilitacion-neuropsicologica-en-la-enfermedad-de-Parkinson-2-1-300x226.webp 300w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2023\/10\/Rehabilitacion-neuropsicologica-en-la-enfermedad-de-Parkinson-2-1-400x300.webp 400w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2023\/10\/Rehabilitacion-neuropsicologica-en-la-enfermedad-de-Parkinson-2-1-800x600.webp 800w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2023\/10\/Rehabilitacion-neuropsicologica-en-la-enfermedad-de-Parkinson-2-1-1024x771.webp 1024w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2023\/10\/Rehabilitacion-neuropsicologica-en-la-enfermedad-de-Parkinson-2-1.webp 1200w\" sizes=\"(max-width:599px) 599px, (min-width:600px) and (max-width: 799px) 799px, (min-width:800px) and (max-width: 999px) 333px, (min-width:1000px) 400px\" \/><\/a><div class=\"entry-wrap entry-wrap-grid\"><h3 class=\"entry-title\" itemprop=\"headline\"><a class=\"entry-title-link\" href=\"https:\/\/neuronup.com\/br\/noticias-de-estimulacao-cognitiva\/doencas-neurodegenerativas\/parkinson\/reabilitacao-neuropsicologica-na-doenca-de-parkinson\/\" rel=\"bookmark\">Reabilita\u00e7\u00e3o neuropsicol\u00f3gica na doen\u00e7a de Parkinson<\/a><\/h3>\n<\/div><\/article><article class=\"entry entry-grid is-column has-entry-link has-image has-image-first type-post category-parkinson tag-parkinson\" style=\"--entry-index:3;\" aria-label=\"Cheiro de Parkinson\" itemscope itemtype=\"https:\/\/schema.org\/CreativeWork\"><a class=\"entry-image-link\" href=\"https:\/\/neuronup.com\/br\/noticias-de-estimulacao-cognitiva\/doencas-neurodegenerativas\/parkinson\/odor-a-parkinson\/\" tabindex=\"-1\" aria-hidden=\"true\"><img decoding=\"async\" width=\"400\" height=\"300\" src=\"https:\/\/neuronup.com\/br\/wp-content\/uploads\/2023\/04\/olor-a-parkinson-400x300.webp\" class=\"entry-image size-landscape-sm\" alt=\"M\u00e3os entrela\u00e7adas em primeiro plano, uma pessoa idosa e outra mais jovem, com fundo desfocado.\" srcset=\"https:\/\/neuronup.com\/br\/wp-content\/uploads\/2023\/04\/olor-a-parkinson-400x300.webp 400w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2023\/04\/olor-a-parkinson-800x600.webp 800w\" sizes=\"(max-width:599px) 599px, (min-width:600px) and (max-width: 799px) 799px, (min-width:800px) and (max-width: 999px) 333px, (min-width:1000px) 400px\" \/><\/a><div class=\"entry-wrap entry-wrap-grid\"><h3 class=\"entry-title\" itemprop=\"headline\"><a class=\"entry-title-link\" href=\"https:\/\/neuronup.com\/br\/noticias-de-estimulacao-cognitiva\/doencas-neurodegenerativas\/parkinson\/odor-a-parkinson\/\" rel=\"bookmark\">Cheiro de Parkinson<\/a><\/h3>\n<\/div><\/article><article class=\"entry entry-grid is-column has-entry-link has-image has-image-first type-post category-parkinson tag-enfermedades-neurodegenerativas tag-parkinson\" style=\"--entry-index:4;\" aria-label=\"Fen\u00f4menos on-off e wearing-off na doen\u00e7a de Parkinson\" itemscope itemtype=\"https:\/\/schema.org\/CreativeWork\"><a class=\"entry-image-link\" href=\"https:\/\/neuronup.com\/br\/noticias-de-estimulacao-cognitiva\/doencas-neurodegenerativas\/parkinson\/fenomenos-on-off-e-wearing-off-na-doenca-de-parkinson\/\" tabindex=\"-1\" aria-hidden=\"true\"><img decoding=\"async\" width=\"400\" height=\"300\" src=\"https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/05\/closeup-of-support-hands-400x300.webp\" class=\"entry-image size-landscape-sm\" alt=\"Duas m\u00e3os entrela\u00e7adas, uma idosa com rugas e a outra mais jovem, sobre fundo neutro.\" srcset=\"https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/05\/closeup-of-support-hands-400x300.webp 400w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/05\/closeup-of-support-hands-800x600.webp 800w\" sizes=\"(max-width:599px) 599px, (min-width:600px) and (max-width: 799px) 799px, (min-width:800px) and (max-width: 999px) 333px, (min-width:1000px) 400px\" \/><\/a><div class=\"entry-wrap entry-wrap-grid\"><h3 class=\"entry-title\" itemprop=\"headline\"><a class=\"entry-title-link\" href=\"https:\/\/neuronup.com\/br\/noticias-de-estimulacao-cognitiva\/doencas-neurodegenerativas\/parkinson\/fenomenos-on-off-e-wearing-off-na-doenca-de-parkinson\/\" rel=\"bookmark\">Fen\u00f4menos on-off e wearing-off na doen\u00e7a de Parkinson<\/a><\/h3>\n<\/div><\/article><article class=\"entry entry-grid is-column has-entry-link has-image has-image-first type-post category-parkinson tag-actividades-de-estimulacion-cognitiva tag-enfermedades-neurodegenerativas tag-funciones-ejecutivas tag-parkinson\" style=\"--entry-index:5;\" aria-label=\"10 exerc\u00edcios de estimula\u00e7\u00e3o cognitiva para a doen\u00e7a de Parkinson\" itemscope itemtype=\"https:\/\/schema.org\/CreativeWork\"><a class=\"entry-image-link\" href=\"https:\/\/neuronup.com\/br\/noticias-de-estimulacao-cognitiva\/doencas-neurodegenerativas\/parkinson\/10-exercicios-de-estimulacao-cognitiva-para-pessoas-com-parkinson\/\" tabindex=\"-1\" aria-hidden=\"true\"><img decoding=\"async\" width=\"400\" height=\"300\" src=\"https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/03\/Captura-de-pantalla-2021-04-11-a-las-0.22.16-400x300.webp\" class=\"entry-image size-landscape-sm\" alt=\"Captura de tela de um jogo de sopa de letras para estimula\u00e7\u00e3o cognitiva em Parkinson: grade de letras, palavras para encontrar e controles.\" srcset=\"https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/03\/Captura-de-pantalla-2021-04-11-a-las-0.22.16-300x225.webp 300w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/03\/Captura-de-pantalla-2021-04-11-a-las-0.22.16-400x300.webp 400w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/03\/Captura-de-pantalla-2021-04-11-a-las-0.22.16-768x575.webp 768w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/03\/Captura-de-pantalla-2021-04-11-a-las-0.22.16-800x600.webp 800w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/03\/Captura-de-pantalla-2021-04-11-a-las-0.22.16-1024x767.webp 1024w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/03\/Captura-de-pantalla-2021-04-11-a-las-0.22.16-1200x900.webp 1200w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/03\/Captura-de-pantalla-2021-04-11-a-las-0.22.16.webp 1259w\" sizes=\"(max-width:599px) 599px, (min-width:600px) and (max-width: 799px) 799px, (min-width:800px) and (max-width: 999px) 333px, (min-width:1000px) 400px\" \/><\/a><div class=\"entry-wrap entry-wrap-grid\"><h3 class=\"entry-title\" itemprop=\"headline\"><a class=\"entry-title-link\" href=\"https:\/\/neuronup.com\/br\/noticias-de-estimulacao-cognitiva\/doencas-neurodegenerativas\/parkinson\/10-exercicios-de-estimulacao-cognitiva-para-pessoas-com-parkinson\/\" rel=\"bookmark\">10 exerc\u00edcios de estimula\u00e7\u00e3o cognitiva para a doen\u00e7a de Parkinson<\/a><\/h3>\n<\/div><\/article><article class=\"entry entry-grid is-column has-entry-link has-image has-image-first type-post category-parkinson tag-enfermedades-neurodegenerativas tag-linguagem tag-parkinson\" style=\"--entry-index:6;\" aria-label=\"A fonoaudiologia e os transtornos da linguagem na doen\u00e7a de Parkinson\" itemscope itemtype=\"https:\/\/schema.org\/CreativeWork\"><a class=\"entry-image-link\" href=\"https:\/\/neuronup.com\/br\/noticias-de-estimulacao-cognitiva\/doencas-neurodegenerativas\/parkinson\/a-logopedia-e-os-transtornos-da-linguagem-na-parkinson\/\" tabindex=\"-1\" aria-hidden=\"true\"><img decoding=\"async\" width=\"400\" height=\"300\" src=\"https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/02\/closeup-of-support-hands-1-400x300-1-400x300.webp\" class=\"entry-image size-landscape-sm\" alt=\"Primeiro plano de duas m\u00e3os entrela\u00e7adas: uma pessoa idosa com bengala recebe apoio de um cuidador, em um ambiente de cuidado.\" srcset=\"https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/02\/closeup-of-support-hands-1-400x300-1-300x225.webp 300w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/02\/closeup-of-support-hands-1-400x300-1-400x300.webp 400w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/02\/closeup-of-support-hands-1-400x300-1-768x576.webp 768w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/02\/closeup-of-support-hands-1-400x300-1-800x600.webp 800w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/02\/closeup-of-support-hands-1-400x300-1-1024x768.webp 1024w, https:\/\/neuronup.com\/br\/wp-content\/uploads\/2022\/02\/closeup-of-support-hands-1-400x300-1.webp 1200w\" sizes=\"(max-width:599px) 599px, (min-width:600px) and (max-width: 799px) 799px, (min-width:800px) and (max-width: 999px) 333px, (min-width:1000px) 400px\" \/><\/a><div class=\"entry-wrap entry-wrap-grid\"><h3 class=\"entry-title\" itemprop=\"headline\"><a class=\"entry-title-link\" href=\"https:\/\/neuronup.com\/br\/noticias-de-estimulacao-cognitiva\/doencas-neurodegenerativas\/parkinson\/a-logopedia-e-os-transtornos-da-linguagem-na-parkinson\/\" rel=\"bookmark\">A fonoaudiologia e os transtornos da linguagem na doen\u00e7a de Parkinson<\/a><\/h3>\n<\/div><\/article><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>A doen\u00e7a de Parkinson \u00e9 classificada dentro dos transtornos do movimento, mas hoje sabemos que \u00e9 muito mais do que isso. Trata-se de uma doen\u00e7a neurodegenerativa cr\u00f4nica e progressiva que, al\u00e9m de alterar o controle motor, pode provocar sintomas cognitivos, emocionais, do sono, auton\u00f4micos e sensoriais. Seu impacto n\u00e3o se limita \u00e0 mobilidade, podendo afetar &hellip;<\/p>\n","protected":false},"author":1,"featured_media":34581,"parent":32443,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"nup-style","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"class_list":["page","type-page","entry"],"acf":[],"_links":{"self":[{"href":"https:\/\/neuronup.com\/br\/wp-json\/wp\/v2\/pages\/34579","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neuronup.com\/br\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/neuronup.com\/br\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/neuronup.com\/br\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/neuronup.com\/br\/wp-json\/wp\/v2\/comments?post=34579"}],"version-history":[{"count":1,"href":"https:\/\/neuronup.com\/br\/wp-json\/wp\/v2\/pages\/34579\/revisions"}],"predecessor-version":[{"id":53073,"href":"https:\/\/neuronup.com\/br\/wp-json\/wp\/v2\/pages\/34579\/revisions\/53073"}],"up":[{"embeddable":true,"href":"https:\/\/neuronup.com\/br\/wp-json\/wp\/v2\/pages\/32443"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neuronup.com\/br\/wp-json\/wp\/v2\/media\/34581"}],"wp:attachment":[{"href":"https:\/\/neuronup.com\/br\/wp-json\/wp\/v2\/media?parent=34579"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}